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Antigenic Specificity | TLR3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR3. |
Other Names | [Toll-like receptor 3] |
Gene, Accession # | [TLR3], Gene ID: 7098, NCBI: NP_003256.1, UniProt: O15455 |
Catalog # | MBS9402035 |
Price | $320 |
Order / More Info | TLR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |