NEDD8 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | NEDD8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total NEDD8 protein. Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Margaret A. Read, Mol. Cell. Biol., Apr 2000; 20: 2326 - 2333. Kenneth Wu, J. Biol. Chem., Aug 2003; 278: 28882 - 28891. Katsumi Kito, J. Biol. Chem., Jun 2001; 276: 20603 - 20609. |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human NEDD8. |
| Other Names | [NED8; NEDD-8; Ubiquitin-like protein NEDD8] |
| Gene, Accession # | [NEDD8], Gene ID: 4738, NCBI: NP_006147.1, UniProt: Q15843 |
| Catalog # | MBS9400790 |
| Price | $200, $255 |
| Order / More Info | NEDD8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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