TANK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTANK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionTANK Antibody: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-κB. This activation of NF-κB occurs through an association with the kinases IKKε and TBK1. More recently, it was shown that these proteins can then form a complex with NEMO, a protein that regulates the activity of the IκB complex. This suggests that in addition to the possibility that TBK1 and IKKε activate the IKKs, the association with the IK
ImmunogenImmunogen: TANK antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human TANK. Buffer: TANK Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[TANK; ITRAF; TRAF2; I-TRAF; ITRAF; TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; TRAF family member-associated NFKB activator], [TANK; TANK; ITRAF; TRAF2; I-TRAF; ITRAF; TRAF2; I-TRAF]
Gene, Accession #[TANK], Gene ID: 10010, NCBI: NP_004171, UniProt: Q92844
Catalog #MBS150385
Price$375
Order / More InfoTANK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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