RP2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RP2 |
| Clone | [3D7] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2b |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for RP2 detection. Tested with WB, FCM in Human; Mouse; Rat.Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segm |
| Immunogen | Immunogen: E. coli-derived human RP2 recombinant protein (Position: D244-M348). |
| Other Names | [Protein XRP2; RP2] |
| Gene, Accession # | [RP2], Gene ID: 6102, NCBI: O75695.4, UniProt: O75695 |
| Catalog # | MBS1752901 |
| Price | $280 |
| Order / More Info | RP2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chapple, J. P., Hardcastle, A. J., Grayson, C., Spackman, L. A., Willison, K. R., Cheetham, M. E.Mutations in the N-terminus of the X-linked retinitis pigmentosa protein RP2 interfere with the normal targeting of the protein to the plasma membrane. Hum. Molec. Genet. 9: 1919-1926, 2000. 2. Evans, R. J., Schwarz, N., Nagel-Wolfrum, K., Wolfrum, U., Hardcastle, A. J., Cheetham, M. E.The retinitis pigmentosa protein RP2links pericentriolar vesicle transport between the Golgi and the primary cilium. Hum. Molec. Genet. 19: 1358-1367, 2010. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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