CDK5R1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCDK5R1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total CDK5R1 protein. p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.Tsai L.-H., Nature 371:419-423(1994).Patrick G.N., Nature 402:615-622(1999).Kesavapany S., J. Neurosci. 24:4421-4431(2004).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CDK5R1.
Other Names[CD5R; CD5R1; CDK5 activator 1; CDK5R; Cyclin-dependent kinase 5 activator 1 precursor]
Gene, Accession #[CDK5R1], Gene ID: 8851, NCBI: NP_003876.1, UniProt: Q15078
Catalog #MBS9404625
Price$200, $255
Order / More InfoCDK5R1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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