CD300 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD300 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mg |
| Concentration | 0.5 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Overview: Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:15549731). Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands (PubMed:24035150). May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediat |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 230-290 on human CMRF35-like molecule 1/CD300LF. Conjugation: Unconjugated |
| Other Names | [Affinity Purified CMRF35-like molecule 1/CD300LF; CD300 antigen like family member; CD300 antigen-like family member F; CD300f; CD300LF; CLM; CLM-1; CMRF35-like molecule 1; IGSF; IgSF13; Immune receptor expressed on myeloid cells 1; immunoglobin superfamily member; Immunoglobulin superfamily member 13; Inhibitory receptor IREM1; IREM; IREM-1; Nepmucin; NK inhibitory receptor; NKIR; TREM; triggering receptors expressed on myeloid cells; UNQ3105/PRO10111] |
| Gene, Accession # | [CD300], Gene ID: 146722, NCBI: NP_001276011.1, UniProt: Q8TDQ1 |
| Catalog # | MBS5400360 |
| Price | $390 |
| Order / More Info | CD300 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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