ASK1 (pSer966) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASK1 (pSer966)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (expected from sequence)
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRabbit anti ASK1 (pSer966) antibody recognizes apoptosis signal-regulating kinase 1 (ASK1), also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5) and MAPK/ERK kinase kinase 5 (MEKK 5), when phosphorylated at serine 966. ASK1 is a serine/threonine kinase that plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. When phosphorylated at serine 966, ASK1 interacts with 14-3-3 protein family members, inhibiting ASK1 mediated apoptosis. ASK1 is dephosphorylated at serine 966 in response to H2O2, activating ASK1(Goldman and Chen 2004).
ImmunogenImmunogen: Phospho specific-peptide corresponding to residues surrounding serine 966 of human ASK1
Other Names[ASK1 (pSer966)], [MAP3K5; MAP3K5; ASK1; MEKK5; MAPKKK5; ASK1; MAPKKK5; MEKK5; ASK-1; MEK kinase 5; MEKK 5]
Gene, Accession #[MAP3K5], Gene ID: 4217, NCBI: Q99683.1, UniProt: Q99683
Catalog #MBS225188
Price$375
Order / More InfoASK1 (pSer966) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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