HSP70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSP70
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatPEG purified
Size0.025 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA (EIA)
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DescriptionDetects ~70kDa. HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (1). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (2). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP binding activity was found
ImmunogenImmunogen: Full length Human HSP70 Immunogen Species: Human
Other Names[Chicken Human HSP70; HSP70 1; HSP70 2; HSP70.1; HSP72; HSPA1; HSPA1A; HSPA1B]
Gene, Accession #[HSP70], Gene ID: 3303, NCBI: NP_005336.3, UniProt: P0DMV8
Catalog #MBS8002016
Price$245
Order / More InfoHSP70 Antibody from MYBIOSOURCE INC.
Product Specific References1. Balashova N. et al. (2005) J Biol Chem 280: 2186-96. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol.38 (1): 1-17. 3. Rothman J. (1989) Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Natl Acad. Sci. USA 89: 7290-7294. 6. Fink A.L. (1999) Physiol. Rev. 79: 425-449.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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