CD11b/MAC-1 (Microglial Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD11b/MAC-1 (Microglial Marker)
Clone[ITGAM/3340]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin aM combines with the Integrin '2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin aM/'2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part
ImmunogenImmunogen: Recombinant fragment (around aa941-1074) of human ITGAM protein (exact sequence is proprietary)
Other Names[CD18; CD49d; Cell surface glycoprotein MAC-1 subunit alpha; Complement Component Receptor 3 Alpha; CR3 Alpha Chain (CR3A); Integrin alpha-M; Integrin beta 2 alpha subunit; Leukocyte adhesion receptor MO1; Ly-40; MAC1A; Macrophage antigen alpha polypeptide; MO1A; Neutrophil adherence receptor alpha M subunit]
Gene, Accession #[CD11b/MAC-1], Gene ID: 3684, NCBI: NP_001139280.1, UniProt: P11215
Catalog #MBS4381023
Price$190, $340, $340
Order / More InfoCD11b/MAC-1 (Microglial Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSpringer T, et al. 1978. Eur. J. Immunol. 8:539
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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