PRDM16 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPRDM16
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPRDM16 Antibody: PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway.
ImmunogenImmunogen: PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16. Buffer: PRDM16 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PRDM16; MEL1; LVNC8; PFM13; CMD1LL; KIAA1675; MEL1; PR domain zinc finger protein 16; PR domain-containing protein 16; PR domain containing 16], [PRDM16; PRDM16; MEL1; LVNC8; PFM13; CMD1LL; KIAA1675; MEL1; PFM13; MDS1/EVI1-like gene 1]
Gene, Accession #[PRDM16], Gene ID: 63976, NCBI: CAH71530, UniProt: Q9HAZ2
Catalog #MBS150905
Price$375
Order / More InfoPRDM16 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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