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Antigenic Specificity | NLGN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NLGN2 antibody detects endogenous levels of total NLGN2. Function: Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal s |
Immunogen | Immunogen: A synthesized peptide derived from human NLGN2 Subcellular Location: Cell Membrane Tissue Specificity: Expressed in the blood vessel walls. Detected in colon, brain and pancreas islets of Langerhans (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells. Predicted Cross Reactivity: Bovine, Horse, Rabbit, Dog Similarity: Bovine (80%), Horse (90%), Rabbit (90%), Dog (90%) |
Other Names | [KIAA1366; MGC67386; NL2; NLGN2; Ortholog of human and rat neuroligin 2 NLGN2; OTTHUMP00000135277; OTTMUSP00000006214; RP23-422L16.24] |
Gene, Accession # | [NLGN2], Gene ID: 57555, NCBI: NP_065846.1, UniProt: Q8NFZ4 |
Catalog # | MBS9610008 |
Price | $240, $280 |
Order / More Info | NLGN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |