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Antigenic Specificity | ITGAL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant Protein of human ITGAL Observed Molecular Weight: 129kDa |
Other Names | [CD11A; LFA-1; LFA1A] |
Gene, Accession # | [ITGAL], Gene ID: 3683, NCBI: NP_001107852.1 |
Catalog # | MBS2519581 |
Price | $150, $225, $360 |
Order / More Info | ITGAL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |