Edit |   |
---|---|
Antigenic Specificity | Nestin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Nestin antibody detects endogenous levels of total Nestin. Function: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).Subunit Structure: Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does n |
Immunogen | Immunogen: A synthesized peptide derived from human Nestin Tissue Specificity: CNS stem cells. Predicted Cross Reactivity: Rabbit, Dog Similarity: Rabbit (93%), Dog (86%) |
Other Names | [ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin] |
Gene, Accession # | [NES], Gene ID: 10763, NCBI: NP_006608.1, UniProt: P48681 |
Catalog # | MBS9608331 |
Price | $240, $280 |
Order / More Info | Nestin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |