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Antigenic Specificity | PKC zeta (N-term), 166-197 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PKC zeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta. Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related |
Immunogen | n/a |
Other Names | [Protein kinase C zeta type; nPKC-zeta; PRKCZ; PKC2] |
Gene, Accession # | [PRKCZ], Gene ID: 5590, NCBI: NP_001028753.1, UniProt: Q05513 |
Catalog # | MBS9209322 |
Price | $165, $370 |
Order / More Info | PKC zeta (N-term), 166-197 Antibody from MYBIOSOURCE INC. |
Product Specific References | Li, Y.F., et al., World J. Gastroenterol. 9(9):2078-2082 (2003). Minami, T., et al., J. Biol. Chem. 278(9):6976-6984 (2003). Beeson, M., et al., Diabetes 52(8):1926-1934 (2003). Laudanna, C., et al., Lab. Invest. 83(8):1155-1163 (2003). Dada, L.A., et al., J. Clin. Invest. 111(7):1057-1064 (2003). |