Mouse VEGFR-2/Flk-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse VEGFR-2/Flk-1
Clone[IgG; 3C8]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG1
FormatProtein G purified
Size0.05 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe unconjugated antibody will detect native mouse VEGFR-2/Flk-1 in Western analysis. Disruption of the precise balance of positi ve and negative molecular regulators of blood and lymphatic vesse l growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vesse l growth has not to our knowledge been previou sly described. A splice variant of the gene encoding vascular endothelial growth factor receptor-2 (VEGFR-2) that encodes a secreted form of the protein. designated endogenous soluble VEGFR-2 (esV EG FR- 2/KDR) has been described. The endogenous soluble esKDR inhibits developmental and reparative Iymphangiogenes is by blocking VEGF-C f
ImmunogenImmunogen: murine stromal cell line. Conjugation: Biotin. Preparation: Monoclonal antibodies were produced with the help of BALB/c mice using recombinant mouse soluble extracellular Flk-1 as the immunizing antigen
Other Names[mouse VEGFR-2/Flk-1-Biotin (#3C8); Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1], [Kdr; Kdr; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; Flk-1; Flk1; VEGFR-2; FLK-1]
Gene, Accession #[VEGFR-2/Flk-1], Gene ID: 16542, NCBI: ACJ66293.1, UniProt: P35918
Catalog #MBS690969
Price$345
Order / More InfoMouse VEGFR-2/Flk-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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