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Antigenic Specificity | Mouse VEGFR-2/Flk-1 |
Clone | [IgG; 3C8] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The unconjugated antibody will detect native mouse VEGFR-2/Flk-1 in Western analysis. Disruption of the precise balance of positi ve and negative molecular regulators of blood and lymphatic vesse l growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vesse l growth has not to our knowledge been previou sly described. A splice variant of the gene encoding vascular endothelial growth factor receptor-2 (VEGFR-2) that encodes a secreted form of the protein. designated endogenous soluble VEGFR-2 (esV EG FR- 2/KDR) has been described. The endogenous soluble esKDR inhibits developmental and reparative Iymphangiogenes is by blocking VEGF-C f |
Immunogen | Immunogen: murine stromal cell line. Conjugation: Biotin. Preparation: Monoclonal antibodies were produced with the help of BALB/c mice using recombinant mouse soluble extracellular Flk-1 as the immunizing antigen |
Other Names | [mouse VEGFR-2/Flk-1-Biotin (#3C8); Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1], [Kdr; Kdr; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; Flk-1; Flk1; VEGFR-2; FLK-1] |
Gene, Accession # | [VEGFR-2/Flk-1], Gene ID: 16542, NCBI: ACJ66293.1, UniProt: P35918 |
Catalog # | MBS690969 |
Price | $345 |
Order / More Info | Mouse VEGFR-2/Flk-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008). |