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Antigenic Specificity | Caveolin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caveolin-1 Polyclonal Antibody detects endogenous levels of Caveolin-1 protein. The scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Caveolin-1 at AA range: 100-180 |
Other Names | [Rabbit Caveolin-1; CAV; Caveolin-1] |
Gene, Accession # | [CAV1], Gene ID: 857, NCBI: NP_001744.2, UniProt: Q03135 |
Catalog # | MBS9700660 |
Price | $250, $250 |
Order / More Info | Caveolin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |