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Antigenic Specificity | CHRNA2 (N-term), 42-69 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CHRNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the N-terminal region of human CHRNA2. Nicotinic acetylcholine receptors (nAChRs) areligand-gated ion channels formed by a pentameric arrangement ofalpha and beta subunits to create distinct muscle and neuronalreceptors. Neuronal receptors are found throughout the peripheraland central nervous system where they are involved in fast synaptictransmission. This gene encodes an alpha subunit that is widelyexpressed in the brain. The proposed structure for nAChR subunitsis a conserved N-terminal extracellular domain followed by threeconserved transmembrane domains, a variable cytoplasmic |
Immunogen | n/a |
Other Names | [Neuronal acetylcholine receptor subunit alpha-2; CHRNA2] |
Gene, Accession # | [CHRNA2], Gene ID: 1135, NCBI: NP_000733.2, UniProt: Q15822 |
Catalog # | MBS9209939 |
Price | $165, $370 |
Order / More Info | CHRNA2 (N-term), 42-69 Antibody from MYBIOSOURCE INC. |
Product Specific References | Saccone, N.L., et al. Genes Brain Behav. 9(7):741-750(2010) Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010) Rigbi, A., et al. Pharmacogenomics J. (2010) In press : Hoda, J.C., et al. FEBS Lett. 583(10):1599-1604(2009) Philibert, R.A., et al. Nicotine Tob. Res. 11(3):286-292(2009) |