PSEN2 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSEN2 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis is a rabbit polyclonal antibody against PSEN2. It was validated on Western Blot and immunohistochemistryTarget Description: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or t
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSEN2
Other Names[presenilin-2 isoform 1; Presenilin-2; presenilin-2; presenilin 2; AD3LP; AD5; E5-1; STM-2]
Gene, Accession #[PSEN2], Gene ID: 5664, NCBI: NP_000438, UniProt: P49810
Catalog #MBS3207300
Price$365
Order / More InfoPSEN2 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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