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Antigenic Specificity | Phospho-SYK (Ser297) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Syk (Ser297) antibody detects endogenous levels of Syk. Function: Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The pho |
Immunogen | Immunogen: A synthesized peptide derived from human Syk around the phosphorylation site of Ser297. Subcellular Location: Cell Membrane. Cytoplasm, Cytosol. Tissue Specificity: Widely expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is for instance expressed for pro-B-cells to plasma cells. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit Similarity: Pig (100%), Horse (100%), Sheep (83%), Rabbit (100%) |
Other Names | [EC 2.7.10.2; kinase Syk; KSYK; KSYK_HUMAN; p72-Syk; p72syk; Spleen tyrosine kinase; Syk; Tyrosine protein kinase SYK; Tyrosine-protein kinase SYK] |
Gene, Accession # | [SYK], Gene ID: 6850, NCBI: NP_001128524.1, UniProt: P43405 |
Catalog # | MBS9600743 |
Price | $240, $280 |
Order / More Info | Phospho-SYK (Ser297) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |