Nanog Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNanog
Clone[5A10]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG2a, k
FormatProtein G purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
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DescriptionNanog is a multidomain homeobox transcription factor that functions to maintain the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. When Nanog expression is downregulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
ImmunogenImmunogen: Recombinant human Nanog (1-154aa) purified from E. coli
Other Names[Nanog homeobox,FLJ12581; FLJ40451], [NANOG; NANOG; hNanog]
Gene, Accession #[Nanog], Gene ID: 79923, NCBI: NP_079141, UniProt: Q9H9S0
Catalog #MBS200100
Price$240, $315
Order / More InfoNanog Antibody from MYBIOSOURCE INC.
Product Specific ReferencesTay Y., et al. (2008) Nature. 455 (7216):1124-8; Chiou SH., et al. (2008) Clin Cancer Res. 14 (13):4085-95; Boer B., et al. (2008) Mol Reprod Dev.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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