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Antigenic Specificity | Nanog |
Clone | [5A10] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nanog is a multidomain homeobox transcription factor that functions to maintain the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. When Nanog expression is downregulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. |
Immunogen | Immunogen: Recombinant human Nanog (1-154aa) purified from E. coli |
Other Names | [Nanog homeobox,FLJ12581; FLJ40451], [NANOG; NANOG; hNanog] |
Gene, Accession # | [Nanog], Gene ID: 79923, NCBI: NP_079141, UniProt: Q9H9S0 |
Catalog # | MBS200100 |
Price | $240, $315 |
Order / More Info | Nanog Antibody from MYBIOSOURCE INC. |
Product Specific References | Tay Y., et al. (2008) Nature. 455 (7216):1124-8; Chiou SH., et al. (2008) Clin Cancer Res. 14 (13):4085-95; Boer B., et al. (2008) Mol Reprod Dev. |