Edit |   |
---|---|
Antigenic Specificity | H2AFX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Histone H2A.X: H2A.X; H2A/X; H2AX], [H2AFX; H2AFX; H2AX; H2A.X; H2A/X; H2AX; H2a/x] |
Gene, Accession # | [H2AFX], Gene ID: 3014, NCBI: P16104.2, UniProt: P16104 |
Catalog # | MBS125454 |
Price | $275, $430 |
Order / More Info | H2AFX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |