SHANK3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SHANK3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mg |
| Concentration | 0.5 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Overview: Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1600-1650 on mouse SH3 and multiple ankyrin repeat domains protein 3. Conjugation: Unconjugated |
| Other Names | [Affinity Purified SH3 and multiple ankyrin repeat domains protein 3; AI841104; DEL22q13.3; KIAA1650; Proline-rich synapse-associated protein 2; PSAP2; SH3 and multiple ankyrin repeat domains 3; SH3/ankyrin domain gene 3; SHAN3_HUMAN; Shank postsynaptic density protein; Shank3; Shank3b; SPANK 2] |
| Gene, Accession # | [SHANK3], Gene ID: 58234, NCBI: NP_067398.2, UniProt: Q4ACU6 |
| Catalog # | MBS5400798 |
| Price | $390 |
| Order / More Info | SHANK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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