HP1 alpha (Ab-92) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HP1 alpha (Ab-92) antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | HP1 alpha (Ab-92) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total HP1 alpha protein. Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.Saunders W.S., J. Cell Sci. 104:573-582(1993).The MGC Project Team; Genome Res. 14:2121-2127(2004).Ye Q., J. Biol. Chem. 271:14653-14656(1996). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human HP1 alpha around the phosphorylation site of serine 92 (R-K-S(p)-N-F). |
| Other Names | [antigen p25; chromobox protein homolog 5; heterochromatin protein 1 alpha; HP1 alpha; HP1A] |
| Gene, Accession # | [HP1 alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
| Catalog # | MBS9406277 |
| Price | $200, $255 |
| Order / More Info | HP1 alpha (Ab-92) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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