CRTC2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CRTC2 |
| Clone | [5B10] |
| Host Species | Mouse |
| Reactive Species | human, monkey |
| Isotype | IgG1 |
| Format | ascites |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Glucose homeostasis is regulated by hormones and cellular energy status. Elevations of blood glucose during feeding stimulate insulin release from pancreatic beta-cells through a glucose sensing pathway. Feeding also stimulates release of gut hormones such as glucagon-like peptide-1 (GLP-1), which further induces insulin release, inhibits glucagon release and promotes beta-cell viability. CREB-dependent transcription likely plays a role in both glucose sensing and GLP-1 signaling. The protein Torc2 (transducer of regulated CREB activity 2) functions as a CREB co-activator and is implicated in mediating the effects of these two pathways. In quiescent cells, Torc2 is phosphorylated at Ser171 and becomes sequestered in the cytoplasm via an int |
| Immunogen | Immunogen: Purified recombinant fragment of human CRTC2 expressed in E. Coli. |
| Other Names | [TORC2; TORC-2; CRTC2] |
| Gene, Accession # | [CRTC2], Gene ID: 200186, NCBI: NP_859066, UniProt: Q53ET0 |
| Catalog # | MBS8538698 |
| Price | $280 |
| Order / More Info | CRTC2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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