EPS8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | EPS8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: EPS8 antibody detects endogenous levels of total EPS8. Function: Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulat |
| Immunogen | Immunogen: A synthesized peptide derived from human EPS8 Subcellular Location: Plasma Membrane Tissue Specificity: Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Horse (89%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100 |
| Other Names | [Epidermal growth factor receptor kinase substrate 8; Epidermal growth factor receptor pathway substrate 8; EPS 8; EPS8; EPS8_HUMAN] |
| Gene, Accession # | [EPS8], Gene ID: 2059, NCBI: NP_004438.3, UniProt: Q12929 |
| Catalog # | MBS9608776 |
| Price | $240, $280 |
| Order / More Info | EPS8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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