Human CD25 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD25
Clone[4A7G7B6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatfluorescein (FITC) conjugate
Size50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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Description4A7G7B6 reacts with CD25 antigen, a chain of low-affinity interleukin-2 receptor (IL-2Ra), which is expressed on activated cells including T, B, NK cells and monocytes. The antigen also prsent on subset of thymocytes, HTLV-1 transformed T cell lines, EBV transformed B cells, myeloid precursors and oligodendrocytes. The high affinity IL-2 receptor is formed by the noncovalent association of of a (55 kDa, CD25), b (75 kDa, CD122), and g subunit (70 kDa, CD132). The interaction of IL-2 with IL-2R induces the activation and proliferation of T, B, NK cells and macrophages. CD4+/CD25+ cells might directly regulate the function of responsive T cells.
Immunogenn/a
Other Names[CD25; Peripheral myelin protein 22; Protein CD25; SR13 myelin protein; Schwann cell membrane glycoprotein; SAG]
Gene, Accession #[CD25], NCBI: CAA44297.1, UniProt: P25094
Catalog #MBS8500546
Price$215, $280
Order / More InfoHuman CD25 Antibody from MYBIOSOURCE INC.
Product Specific References1. Kishimoto, T. et al. (1998). Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing, Inc. London. 2. Robb RJ. et al. (1984). J. Exp. Med 160:1126. 3. Greene WC and Leonard WJ et al. (1986). Annu. Rev. Immunol. 4:69. 4. Ng WFet al. (2001). Leukemia 98: 2736.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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