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Antigenic Specificity | IRAK [8F1A7] |
Clone | [8F1A7] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κB activation by members in IL-1 family including IL-1 and |
Immunogen | Immunogen: Recombinant protein corresponding to amino acids 618 - 712 of human IRAK. Buffer: IRAK Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IRAK [8F1A7] : IRAK; pelle; interleukin-1 receptor-associated kinase 1], [IRAK1; IRAK1; IRAK; pelle; IRAK; IRAK-1] |
Gene, Accession # | [IRAK1], Gene ID: 3654, NCBI: P51617.2, UniProt: P51617 |
Catalog # | MBS150038 |
Price | $375 |
Order / More Info | IRAK [8F1A7] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |