IRAK [8F1A7] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRAK [8F1A7]
Clone[8F1A7]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatimmunoaffinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionIRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κB activation by members in IL-1 family including IL-1 and
ImmunogenImmunogen: Recombinant protein corresponding to amino acids 618 - 712 of human IRAK. Buffer: IRAK Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IRAK [8F1A7] : IRAK; pelle; interleukin-1 receptor-associated kinase 1], [IRAK1; IRAK1; IRAK; pelle; IRAK; IRAK-1]
Gene, Accession #[IRAK1], Gene ID: 3654, NCBI: P51617.2, UniProt: P51617
Catalog #MBS150038
Price$375
Order / More InfoIRAK [8F1A7] Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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