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Antigenic Specificity | ITPK1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against ITPK1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ITPK1 |
Other Names | [inositol-tetrakisphosphate 1-kinase isoform a; Inositol-tetrakisphosphate 1-kinase; inositol-tetrakisphosphate 1-kinase; inositol-tetrakisphosphate 1-kinase; Inositol 1,3,4-trisphosphate 5/6-kinase] |
Gene, Accession # | [ITPK1], Gene ID: 3705, NCBI: NP_055031, UniProt: Q13572 |
Catalog # | MBS3211985 |
Price | $335 |
Order / More Info | ITPK1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |