Phospho-Bad (S118) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-Bad (S118) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.298 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Bad Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S118 of human Bad. Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin are found to be involved in the regulation of this protein. Bad is phosphorylated on one or more of Ser-75, Ser-99, Ser-118 and Ser-134 in response to survival stimuli, |
| Immunogen | n/a |
| Other Names | [Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BAD; BBC6; BCL2L8] |
| Gene, Accession # | [BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
| Catalog # | MBS9204976 |
| Price | $165, $370 |
| Order / More Info | Phospho-Bad (S118) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hurbin, A., et al., J. Biol. Chem. 280(20):19757-19767 (2005). Antignani, A., et al., Biochemistry 44(10):4074-4082 (2005). Ying, S., et al., Infect. Immun. 73(3):1399-1403 (2005). Seo, S.Y., et al., J. Biol. Chem. 279(40):42240-42249 (2004). Lee, J.W., et al., Carcinogenesis 25(8):1371-1376 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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