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Antigenic Specificity | ING3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ING3 antibody detects endogenous levels of total ING3. Function: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nuclear Tissue Specificity: Expressed in brain, heart, kidney, liver, lung, ovaries, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (83%) |
Other Names | [1300013A07Rik; Eaf 4; Eaf4; FLJ20089; ING 2; ING 3; ING2; ING3; ING3_HUMAN; Inhibitor of growth family member 3; Inhibitor of growth protein 3; MEAF4; p47 ING 3; p47 ING3; p47 regulator protein; p47ING3; p47ING3 protein] |
Gene, Accession # | [ING3], Gene ID: 54556, NCBI: NP_061944.2, UniProt: Q9NXR8 |
Catalog # | MBS9604151 |
Price | $240, $280 |
Order / More Info | ING3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |