Edit |   |
---|---|
Antigenic Specificity | LOXL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression o |
Immunogen | Immunogen: Recombinant Human Lysyl oxidase homolog 2 protein (27-121AA) Conjugation: HRP |
Other Names | [Lysyl oxidase homolog 2; Lysyl oxidase-like protein 2; Lysyl oxidase-related protein 2; Lysyl oxidase-related protein WS9-14; LOXL2] |
Gene, Accession # | [LOXL2], Gene ID: 4017, NCBI: NP_002309.1, UniProt: Q9Y4K0 |
Catalog # | MBS7053402 |
Price | $160, $235 |
Order / More Info | LOXL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |