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Antigenic Specificity | PAX8 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And |
Immunogen | Immunogen: PAX8 fusion protein ag0306 |
Other Names | [PAX8; paired box 8; Paired box protein Pax 8] |
Gene, Accession # | [PAX8], Gene ID: 7849, NCBI: NP_003457.1, UniProt: Q06710 |
Catalog # | MBS2540224 |
Price | $220, $290, $435 |
Order / More Info | PAX8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |