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Antigenic Specificity | IL18 binding protein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Protein Function: Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the |
Immunogen | Immunogen: E Coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193). Subcellular Localization: Secreted. |
Other Names | [Interleukin-18-binding protein; IL-18BP; Interferon gamma-inducing factor-binding protein; Il18bp; Igifbp] |
Gene, Accession # | [Il18bp], Gene ID: 16068, NCBI: NP_034661.1, UniProt: Q9Z0M9 |
Catalog # | MBS1750920 |
Price | $280 |
Order / More Info | IL18 binding protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |