IL18 binding protein Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL18 binding protein
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionDescription: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Protein Function: Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the
ImmunogenImmunogen: E Coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193). Subcellular Localization: Secreted.
Other Names[Interleukin-18-binding protein; IL-18BP; Interferon gamma-inducing factor-binding protein; Il18bp; Igifbp]
Gene, Accession #[Il18bp], Gene ID: 16068, NCBI: NP_034661.1, UniProt: Q9Z0M9
Catalog #MBS1750920
Price$280
Order / More InfoIL18 binding protein Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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