Pro-Survival Bcl-2 Family Antibody Sampler Kit Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPro-Survival Bcl-2 Family Antibody Sampler Kit
Clonen/a
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size1 kit
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionBackground: The Bcl-2 family consists of a number of evolutionarily conserved proteins containing Bcl-2 homology domains (BH) that regulate apoptosis through control of mitochondrial membrane permeability and release of cytochrome c. Four BH domains have been identified (BH1-4) that mediate protein interactions. The family can be separated into three groups based upon function and sequence homology: pro-survival members include Bcl-2, Bcl-xL, Mcl-1, A1 and Bcl-w; pro-apoptotic proteins include Bax, Bak and Bok; and BH3 only proteins Bad, Bik, Bid, Puma, Bim, Bmf, Noxa and Hrk. Interactions between death- promoting and death-suppressing Bcl-2 family members has led to a rheostat model in which the ratio of pro-apoptotic and anti-apoptotic
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS2550096
Price$345
Order / More InfoPro-Survival Bcl-2 Family Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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