Phospho-Cot (T290) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Cot (T290) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. MAP3K8 (Mitogen-Activated Protei |
| Immunogen | Immunogen: Synthesized peptide derived from human Cot around the phosphorylation site of T290. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Calculated MW: 53 kDa Observed MW: 60 kDa Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4 |
| Other Names | [MAP3K8; COT; ESTF; Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2; TPL-2] |
| Gene, Accession # | [Cot], UniProt: P41279 |
| Catalog # | MBS2535471 |
| Price | $110, $150, $225 |
| Order / More Info | Phospho-Cot (T290) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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