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Antigenic Specificity | DHDDS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. |
Immunogen | Immunogen: Recombinant human Dehydrodolichyl diphosphate synthase complex subunit DHDDS protein (1-333AA) |
Other Names | [Dehydrodolichyl diphosphate synthase complex subunit DHDDS Curated; Cis-isoprenyltransferase; CIT; Cis-IPTase; Epididymis tissue protein Li 189m; DHDDS; HDS] |
Gene, Accession # | [DHDDS], Gene ID: 79947, NCBI: NP_001230493.1, UniProt: Q86SQ9 |
Catalog # | MBS7044502 |
Price | $120, $160 |
Order / More Info | DHDDS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |