UNC13D Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-UNC13D antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | UNC13D |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: UNC13D antibody detects endogenous levels of total UNC13D. Function: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells.Subunit Structure: Interacts with DOC2A (By similarity). Interacts with RAB27A.Similarity: The MHD1 and MHD2 domains mediate localization on recycling endosomes and lysosome. Belongs to the unc-13 famil |
| Immunogen | Immunogen: A synthesized peptide derived from human UNC13D Subcellular Location: Endosome; Lysosome Tissue Specificity: Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells. Predicted Cross Reactivity: Pig, Dog Similarity: Pig (100%), Dog (89%) |
| Other Names | [FHL 3; FHL3; FLJ00067; HLH 3; HLH3; HPLH 3; HPLH3; Jinx; Munc13 4; Munc13-4; Protein unc 13 homolog D; Protein unc-13 homolog D; UN13D_HUMAN; Unc 13 homolog D; UNC 13D; Unc-13 homolog D (C. elegans); Unc13 homolog D (C elegans); Unc13 homolog D; UNC13, C. elegans, homolog of, D; UNC13D; Unc13h4] |
| Gene, Accession # | [UNC13D], Gene ID: 201294, NCBI: NP_954712.1, UniProt: Q70J99 |
| Catalog # | MBS9608594 |
| Price | $240, $280 |
| Order / More Info | UNC13D Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies