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Antigenic Specificity | Phospho-b-Catenin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. beta-catenin can be destabilized by GSK-3beta or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in beta-catenin have been found in many tumor cell lines. |
Immunogen | Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser45 of human beta-Catenin |
Other Names | [Beta-catenin; Catenin beta-1; CTNNB], [CTNNB1; CTNNB1; CTNNB; MRD19; armadillo; CTNNB] |
Gene, Accession # | Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222 |
Catalog # | MBS840205 |
Price | $375 |
Order / More Info | Phospho-b-Catenin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |