Phospho-b-Catenin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-b-Catenin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. beta-catenin can be destabilized by GSK-3beta or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in beta-catenin have been found in many tumor cell lines.
ImmunogenImmunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser45 of human beta-Catenin
Other Names[Beta-catenin; Catenin beta-1; CTNNB], [CTNNB1; CTNNB1; CTNNB; MRD19; armadillo; CTNNB]
Gene, Accession #Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222
Catalog #MBS840205
Price$375
Order / More InfoPhospho-b-Catenin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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