PPHLN Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PPHLN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PPHLN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PPHLN antibody detects endogenous levels of total PPHLN. Function: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Prob |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Cytoplasm. In undifferentiated keratinocytes expressed in speckle-type nuclear granules and at the nuclear membrane, but in the differentiated keratinocytes colocalized with periplakin at the cell periphery and at cell-cell junctions. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Sheep, Rabbit, Dog, Chicken Similarity: Pig (92%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%) |
| Other Names | [Gastric cancer antigen Ga50; Periphilin 1; Periphilin-1; PPHLN_HUMAN; PPHLN1] |
| Gene, Accession # | [PPHLN], Gene ID: 51535, NCBI: NP_001137259.1, UniProt: Q8NEY8 |
| Catalog # | MBS9604816 |
| Price | $240, $280 |
| Order / More Info | PPHLN Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies