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Antigenic Specificity | KANK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5; 9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. |
Immunogen | Immunogen: A synthetic peptide of human KANK1. |
Other Names | [KN motif and ankyrin repeat domain-containing protein 1 isoform L; KN motif and ankyrin repeat domain-containing protein 1; KN motif and ankyrin repeat domain-containing protein 1; KN motif and ankyrin repeat domains 1; Ankyrin repeat domain-containing protein 15; Kidney ankyrin repeat-containing protein] |
Gene, Accession # | [KANK1], Gene ID: 23189, NCBI: NP_055973, UniProt: Q14678 |
Catalog # | MBS8571735 |
Price | $280 |
Order / More Info | KANK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |