MOCS3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MOCS3 |
| Clone | [1C5-E8] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b,k |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human MOCS3. Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; |
| Immunogen | Immunogen: Full-length recombinant corresponding to aa1-461 from human MOCS3 (AAH15939) with GST tag. MW of the GST tag alone is 26kD. |
| Other Names | MOCS3 (Adenylyltransferase and Sulfurtransferase MOCS3, Molybdenum Cofactor Synthesis Protein 3, Molybdopterin Synthase Sulfurylase, MPT Synthase Sulfurylase, UBA4, dJ914P20.3, MGC9252) |
| Gene, Accession # | n/a |
| Catalog # | MBS6010496 |
| Price | $580 |
| Order / More Info | MOCS3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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