Human Tissue Factor (TF), Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Tissue Factor (TF), antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Tissue Factor (TF), |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 0.2 mg |
| Concentration | IgG-HRP concentration is mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 14. |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Prior to conjugation, this antibody was specific for tissue factor as demonstrated by immunoelectrophoresis and ELISA. Tissue Factor (TF) is an integral membrane glycoprotein expressed in the plasma membranes of many cell types. It is a single chain molecule of 44 kDa consisting of an extra-cellular domain (residues 1-219), a trans-membrane domain (residues 220-242) and the Cterminal intracellular domain of residues 243-263. Most abundant in the tissue adventitia, TF becomes exposed to blood at the site of vascular injury. The availability of TF is important in initiating coagulation by acting as a receptor for both the zymogen and protease forms of plasma factor VII (F.VII and F.VIIa), as well as mediating the conversion of bo |
| Immunogen | Immunogen: Recombinant human tissue factor. |
| Other Names | n/a |
| Gene, Accession # | NCBI: AAB26854.1 |
| Catalog # | MBS512161 |
| Price | $340 |
| Order / More Info | Human Tissue Factor (TF), Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemerson Y; in Hemostasis and Thrombosis, 3rd Edition, eds. RW Colman, J Hirsh, VJ Marder and EW Salzman, pp. 81-93, J.B. Lippincott Co., Philadelphia, 1994. 2. Neuenschwander PF, Morrissey JH; Deletion of the Membrane Anchoring Region of Tissue Factor Abolishes Autoactivation of F.VII but not Cofactor Function. JBC 267, pp 14477-14482, 1992. 3. Lawson LH, Butenas S, Mann KG; The Evaluation of Complex-dependent Alterations in Human Factor VIIa. JBC 267, pp 4834-4843, 1992. 4. Sambola A, Osende J, Hathcock J, Degen M, Nemerson Y, Fuster V, Crandall J, Badimon JJ; The Role of Risk Factors in the Modulation of Tissue Factor Activity and Blood Thrombogenicity. Circulation 107, pp 973-977, 2003. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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