RMP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | RMP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RMP antibody detects endogenous levels of total RMP. Function: Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.Subunit Structure: Homodimer. Component of the URI complex that contains PFDN2, POLR2E/RPB5, RUVBL2, RUVBL1 and URI1. Interacts with PPP1CC; the interaction is phos |
| Immunogen | Immunogen: A synthesized peptide derived from human RMP Subcellular Location: Nucleus. Cytoplasm. Mitochondrion. Cell Projection > Dendrite. Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 at mitochondrion. Tissue Specificity: Ubiquitous. Expressed in ovarian cancers (at protein level). Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse |
| Other Names | [C19orf2; Chromosome 19 open reading frame 2; NNX3; NNX3 protein; PPP1R19; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RMP; RMP_HUMAN; RNA polymerase II subunit 5 mediating protein; RNA polymerase II subunit 5-mediating protein; RPB5 mediating protein; RPB5-mediating protein; Unconventional prefoldin RPB5 interactor 1; Unconventional prefoldin RPB5 interactor; URI; URI1; URI1, prefoldin-like chaperone] |
| Gene, Accession # | [RMP], Gene ID: 8725, NCBI: NP_001239570.1, UniProt: O94763 |
| Catalog # | MBS9609033 |
| Price | $240, $280 |
| Order / More Info | RMP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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