Edit |   |
---|---|
Antigenic Specificity | AKT1 (pTyr315)/AKT2 (pTyr316)/AKT3 (pTyr312) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti AKT1 (pTyr315)/AKT2 (pTyr316)/AKT3 (pTyr312) antibody recognizes AKT1 when phosphorylated at tyrosine 315, AKT2 when phosphorylated at tyrosine 316 and AKT3 when phosphorylated at tyrosine 312. AKT 1, 2 and 3 are serine/threonine protein kinases that play a key role in the PI3K-Akt signaling pathway, known to regulate cell growth, proliferation and survival. AKT1 is phosphorylated at tyrosine 315 (corresponding to tyrosine 316/312 of AKT2/AKT3 respectively) by Src and PTK6, tyrosine phosphorylation is important for growth factor mediated activation of AKT (Zheng et al. 2010). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 315 of human AKT1/ tyrosine 316 of human AKT2/ tyrosine 312 of human AKT3 |
Other Names | [AKT1 (pTyr315)/AKT2 (pTyr316)/AKT3 (pTyr312)], [AKT2; AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA; PKB beta] |
Gene, Accession # | [AKT2], Gene ID: 208, NCBI: P31751.2, UniProt: P31751 |
Catalog # | MBS225186 |
Price | $375 |
Order / More Info | AKT1 (pTyr315)/AKT2 (pTyr316)/AKT3 (pTyr312) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |