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Antigenic Specificity | DKK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Dickkopf-related protein 1(DKK1) detection. Tested with WB in Human, Mouse, Rat. Background: DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DKK1 (68-83aa YPGGNKYQTIDNYQPY), different from the related mouse and rat sequences by two amino acids. |
Other Names | [Dickkopf-related protein 1(Dickkopf-1/Dkk-1/hDkk-1); dickkopf 1 homolog(Xenopus laevis); Dickkopf 1; Dickkopf 1 homolog; Dickkopf 1 like; Dickkopf homolog 1; Dickkopf like protein 1; Dickkopf related protein 1; Dickkopf-1; Dickkopf-related protein 1; DKK 1; Dkk-1; Dkk1; DKK1_HUMAN; hDkk 1; hDkk-1; hDkk1; SK], [DKK1; DKK1; SK; DKK-1; Dickkopf-1; Dkk-1; hDkk-1] |
Gene, Accession # | [DKK1], Gene ID: 22943, NCBI: O94907.1, UniProt: O94907 |
Catalog # | MBS175281 |
Price | $280 |
Order / More Info | DKK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |