Phospho-ERBB2-Y1248 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ERBB2-Y1248
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding Y1248 of human ERBB2 Calculated Molecular Weight: 185kDa
Other Names[Phospho-ERBB2-Y1248: NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19]
Gene, Accession #[ERBB2], Gene ID: 2064, NCBI: P04626.1, UniProt: P04626
Catalog #MBS128266
Price$235, $350, $525
Order / More InfoPhospho-ERBB2-Y1248 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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