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Antigenic Specificity | Human Thr181 phosphorylated Tau |
Clone | [7G9] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes the above mentioned peptide and its KLH conjugate, but not recognizes KLH alone. The antibody detected a 46kD band in mouse brain tissue lysate. Tau Protein (Thr181 Phosphorylated). Description: Mouse monoclonal antibody against Thr181 phosphorylated Tau protein background: Tau is a highly soluble microtubule associated protein found in high concentration in neuron of central nervous system. The main function of the protein is stabilizing the microtubule in nerve fibre (axon). There are six tau isoforms which are formed by alternate splicing. Hyperphosphorylation of Tau protein results in aggregation and formation of neurofibrillary tangles, which is significantly associated with cognitive impairment in Alzheimer's |
Immunogen | Immunogen: KLH conjugated with a short peptide [Ala-Pro-Lys-Thr(p)-Pro-Pro-Ser-Ser-Gly-Glu-Cys], corresponding to the amino acid sequence 177-187 on the phosphorylated Tau protein. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS592364 |
Price | $445 |
Order / More Info | Human Thr181 phosphorylated Tau Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |