Edit |   |
---|---|
Antigenic Specificity | P2RX7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: P2RX7 antibody detects endogenous levels of total P2RX7. Function: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells (PubMed:21821797, PubMed:23303206).Subunit Structure: Functional P2XRs are organized as homomeric and heteromeric trimers. Interacts with LAMA3, ITGB2, ACTB, ACTN4, SVIL, MPP3, HSPA1, HSPCB, HSPA8, PIK230 and PTPRB. Interacts (via C-terminus) with EMP |
Immunogen | Immunogen: A synthesized peptide derived from human P2RX7 Subcellular Location: Cell Membrane Tissue Specificity: Widely expressed with highest levels in brain and immune tissues. |
Other Names | [ATP receptor; P2rx7; P2RX7_HUMAN; P2X purinoceptor 7; P2X7; P2Z receptor; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 7] |
Gene, Accession # | [P2RX7], Gene ID: 5027, NCBI: NP_002553.3, UniProt: Q99572 |
Catalog # | MBS9608581 |
Price | $240, $280 |
Order / More Info | P2RX7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |