c-IAPS/BIRC3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | c-IAPS/BIRC3 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, monkey |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous levels of BIRC3 and does not cross-react with related proteins. UniPort Summary Function: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis.Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions:acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling.The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, C |
| Immunogen | Immunogen: Purified recombinant c-IAP2 protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Nucleus |
| Other Names | [CIAP 2; Inhibitor of apoptosis protein 1; AIP 1; AIP1; API 2; API2; Apoptosis inhibitor 2; Baculoviral IAP repeat containing 3; Baculoviral IAP repeat-containing protein 3; BIRC 3; BIRC3; C IAP2; CIAP 2; CIAP2; HAIP 1; HAIP1; HIAP1; IAP homolog C; IAP-1; Inhibitor of apoptosis protein 1; MALT 2; MALT2; Mammalian IAP homolog C; MIHC; MIHC; RING finger protein 49; RNF49; TNFR2 TRAF signaling complex protein 1; TNFR2 TRAF signalling complex protein; AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2], [BIRC3; BIRC3; AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2; API2; MIHC; RNF49; hIAP-1; hIAP1] |
| Gene, Accession # | [c-IAPS/BIRC3], Gene ID: 330, NCBI: NP_001156.1, UniProt: Q13489 |
| Catalog # | MBS857747 |
| Price | $300 |
| Order / More Info | c-IAPS/BIRC3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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