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Antigenic Specificity | TIRAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP (NP 001034750.1). |
Other Names | [Mal; wyatt; BACTS1; MyD88-2] |
Gene, Accession # | [TIRAP], Gene ID: 114609, NCBI: NP_001034750.1, UniProt: P58753 |
Catalog # | MBS8544686 |
Price | $280 |
Order / More Info | TIRAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |